The fields that are almost entirely focused on conflicts, where applied mathematics is successfully used, are law, military science, many branches of economics, sociology, political science, and psychology. There are good grounds to believe that medicine and some branches of biology and ethics can also be included in this list. Modern applied mathematics can produce solutions to many tens of classes of conflicts differing by the composition and structure of the participants, specific features of the set of their objectives or interests, and various characteristics of the set of their actions, strategies, behaviors, controls, and decisions as applied to various principles of selection or notions of decision optimization. The current issues of social and economic systems involve the necessity to coordinate and jointly optimize various lines of development and activities of modern society. For this reason, the decision problems arising in investigation of such systems are versatile, which shows up not only in the multiplicity of participants, their interests and complexity of reciprocal effects, but also in the laborious development of social utility criteria for a variety of indices and versatile objectives. The efficient decision methods for such complex systems can be developed only the basis of specially developed mathematical tools.